IBM WebSphere MQ 5.3升级到CSD05之后，提供了使用.net操作MQ的类库，安装完成之后，会在MQ的安装目录的bin文件夹下面多出一个amqmdnet.dll文件，把这个DLL作为引用添加到你的.net工程中，你的.net程序中就可以操作IBM WebSphere MQ。
    我的MQ是中文版的，操作系统是win2k003 sp1，无论是在队列管理器，还是用代码新建的队列，都与我本机时间相差8小时，不晓得何解，哪位高人可以释疑?

//新建本地队列           
PCFMessageAgent agent = new PCFMessageAgent("QM_janus");
            PCFMessage request = new PCFMessage(CMQCFC.MQCMD_CREATE_Q);
            request.AddParameter(MQC.MQCA_Q_NAME, "test_queue");
            request.AddParameter(MQC.MQIA_Q_TYPE, MQC.MQQT_LOCAL);
            //request.AddParameter(MQC.MQIA_USAGE, MQC.MQUS_TRANSMISSION);
            PCFMessage[] response = agent.Send(request);

//删除队列
            PCFMessageAgent agent = new PCFMessageAgent("QM_janus");
            PCFMessage request = new PCFMessage(CMQCFC.MQCMD_DELETE_Q);
            request.AddParameter(MQC.MQCA_Q_NAME, "test_queue");
            PCFMessage[] response = agent.Send(request);

//从队列中读取消息
            MQQueueManager qMgr = new MQQueueManager("QM_janus");
            MQQueue queue = qMgr.AccessQueue("postcard", MQC.MQOO_INPUT_AS_Q_DEF | MQC.MQOO_FAIL_IF_QUIESCING);
            MQGetMessageOptions gmo = new MQGetMessageOptions();
            gmo.Options = MQC.MQGMO_WAIT;
            gmo.WaitInterval = 1000;
            gmo.MatchOptions = MQC.MQMO_NONE;
            MQMessage message = new MQMessage();
            queue.Get(message);
 
 //向队列写消息
            MQQueueManager qMgr = new MQQueueManager("QM_janus");
            MQQueue queue = qMgr.AccessQueue("postcard", MQC.MQOO_OUTPUT);
            MQMessage message = new MQMessage();
            message.WriteString("message body");
            queue.Put(message);

//枚举所有队列
            PCFMessageAgent agent = new PCFMessageAgent("QM_janus");
            PCFMessage request = new PCFMessage(CMQCFC.MQCMD_INQUIRE_Q_NAMES);
            request.AddParameter(MQC.MQCA_Q_NAME, "*");
            PCFMessage[] response = agent.Send(request);
            string[] names = response[0].GetStringListParameterValue(CMQCFC.MQCACF_Q_NAMES);

 http://www.cnblogs.com/janus1999/archive/2006/09/11/501133.html